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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KDM3A All Species: 16.36
Human Site: S461 Identified Species: 40
UniProt: Q9Y4C1 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4C1 NP_001140160.1 1321 147327 S461 E V K A G V N S D S P N N C S
Chimpanzee Pan troglodytes XP_525805 1351 150410 S491 E V K A G V N S D S P N N C S
Rhesus Macaque Macaca mulatta XP_001086319 1444 159442 S584 E V K A G V D S D S P N N C S
Dog Lupus familis XP_532973 1339 149681 S462 E E K A G V V S N S P N S C V
Cat Felis silvestris
Mouse Mus musculus Q6PCM1 1323 147829 V461 K P E V K A G V T S L N S C A
Rat Rattus norvegicus Q63679 1214 135386 K442 L D S L R K D K D Q Q K D S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511537 1285 142386 T451 P W G N S K E T S G C K N E N
Chicken Gallus gallus Q5ZIX8 1325 149315 S469 G V R S H S G S N S Q K G N K
Frog Xenopus laevis Q5HZN1 1334 149927 K484 L S V T D S P K T A L Q K T C
Zebra Danio Brachydanio rerio XP_686742 2513 279609 T1447 P Q A C S A G T P Q A Y S R N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.4 89.9 92.9 N.A. 91.4 83.4 N.A. 74.5 70.1 57.1 25.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.6 90.8 95.5 N.A. 95.7 87.2 N.A. 81.4 79.6 70.3 36.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 66.6 N.A. 20 6.6 N.A. 6.6 20 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 80 N.A. 46.6 20 N.A. 20 40 6.6 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 40 0 20 0 0 0 10 10 0 0 0 10 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 10 0 0 50 10 % C
% Asp: 0 10 0 0 10 0 20 0 40 0 0 0 10 0 0 % D
% Glu: 40 10 10 0 0 0 10 0 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 10 0 40 0 30 0 0 10 0 0 10 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 40 0 10 20 0 20 0 0 0 30 10 0 10 % K
% Leu: 20 0 0 10 0 0 0 0 0 0 20 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 20 0 20 0 0 50 40 10 20 % N
% Pro: 20 10 0 0 0 0 10 0 10 0 40 0 0 0 10 % P
% Gln: 0 10 0 0 0 0 0 0 0 20 20 10 0 0 0 % Q
% Arg: 0 0 10 0 10 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 0 10 10 10 20 20 0 50 10 60 0 0 30 10 30 % S
% Thr: 0 0 0 10 0 0 0 20 20 0 0 0 0 10 0 % T
% Val: 0 40 10 10 0 40 10 10 0 0 0 0 0 0 10 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _